Searchable abstracts of presentations at key conferences in endocrinology

ea0034oc6.4 | Clinical | SFEBES2014

Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome

Udiawar Maneesh , Berlot Rok , O'Sullivan Michael , Rees Aled

Background: Metabolic disorders such as type 2 diabetes are risk factors for the development of dementia. In addition to vascular dysfunction, insulin resistance may be important since altered insulin sensitivity is associated with changes in neurogenesis. Polycystic ovary syndrome (PCOS) is a disorder characterised by insulin resistance. Little is known about the impact of metabolic abnormalities on brain structure and function in younger adults.Objecti...